DMAA

Almost every supplement or pro-hormone that really worked was banned, what we see now, more and more, is that FDA finds spiked supplements.

The  war on drugs is about to include supplements and is just going to bring down more FDA control of supplements, Matt Cahill a designer supplements manufacturer sold DMAA – SuperDrol and DNP. Now it seems Craze was spiked also.

Bodybuilders use PWO’s (pre work outs), mostly things like cialis to get a better pump. From the day I started to work with weights, I know that a few cups of strong black coffee would help during my work-out, many even use a lotta sugar in it but I don’t like sugar at all.

 If you google on spiked supplements you realize it is a known problem, not only in bodybuilding supplements and pwo’s but also in dietary supplements  -vitamins- sexual-enhancement supplements and especially in weight loss supplements. Part of the appeal of supplements is their apparent naturalness, so they often have a veneer of being safer than prescription drugs.

A case of toxicity from DMAA party pills in New Zealand

This is  an incident but since we post a lot about DMAA I thought to let you know

‘Party pills’ are synthetic stimulants that emerged in New Zealand in the early 2000s. Most were 1-benzylpiperazine (BZP)-based and were widely consumed. Evidence accumulated of risk and toxicity and BZP was subsequently scheduled.1,3

Dimethylamylamine (DMAA) is one of the next generation of ‘BZP-free’ party pills.

This report describes a case of a serious complication associated with the recreational use of DMAA.

Case report

A 21-year-old man was out with friends and purchased a quantity of legal party pills identified as ’99.9%-pure DMAA’. He took the recommended dose of 2 tablets at approximately 11:30 pm along with a capsule identified as 150 mg of caffeine. He had already ingested 1 can of beer.

Within 30 minutes he developed a severe global headache and called for a friend to take him home. He subsequently became confused, incontinent of urine and vomited for 2–3 hours before falling asleep. The next morning he was drowsy and had slurred speech. He did not improve during the day so at 6 pm he was taken to the local hospital emergency department (ED).

Figure 1. DMAA capsules and packaging (brand name obscured)

On arrival in the ED he was confused and had slurred speech. He was disorientated in time but not person or place. He could not give a coherent history. He had a right facial droop and right-sided weakness. There was no sympathomimetic toxicity evident, however 19 hours had elapsed since ingestion. His heart rate was 65 bpm and blood pressure was 126/66 mmHg.

Geranium oils do not contain the stimulant DMAA-MHA, according to new research that once again questions the study often cited by pre-workout and weight loss supplements claiming it does.

Geranium. Not a DMAA-MHA source, researchers have concluded. This makes a ban of synthetic DMAA logical. This supplement seem to work well as a supplementation in fatloss appetite surpression, pre-workout booster and also as a "herbal XTC".

After an analysis of the Chinese study (Ping et al), along with geranium oils, DMAA (1,3 dimethylamylamine)-MHA (methylhexanamine) ingredients and four supplements containing them, the researchers concluded the labelling practice was a “marketing ploy”.

The researchers, led by Angelo Lisi from the National Measurement Institute in Australia, also said the status of another “doping agent” called a and b-phenethylamine needed investigating.

Class action more pressure against DMAA

The regulatory status and safety of DMAA, a stimulant used in sports and weight loss supplements and reported by some to be a natural constituent of geranium oil, has been challenged again.

There is an ongoing debate about whether DMAA (1,3-Dimethyl-amylamine - also known as methyl-hexaneamine or MHA), which was first manufactured synthetically by drug giant Eli Lily in the 1940s, is in fact a constituent of geranium, with the consensus growing that it is not. Health Canada recently issued a statement arguing that DMAA is not found naturally in geranium (as many supplement makers using it claim) and affirming that any products containing it require a drug authorization.